AboutRecurrent Pericarditis
For many individuals, the first acute episode of pericarditis is just the beginning, with up to 30% of these patients experiencing a first recurrence within 18 months.1
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Burden ofDisease
The impact of recurrent pericarditis often extends beyond cardiac effects, with the general uncertainty of each recurrence triggering anxiety, depression, and disruption in overall quality of life.4,5
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PathophysiologyOf Disease
When IL-1 swarms the pericardium, pericarditis recurs. Idiopathic recurrent pericarditis is one of many disorders where reducing IL-1 activity can be effective, suggesting it is the primary mediator of this disease.1-3
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Diagnosis andTreatment
No treatment guidelines have been issued in the US; however, many experts have adopted a stepwise approach based on guidelines from the European Society of Cardiology (ESC),6 employing therapies approved for other conditions to treat symptoms, which may not always address the underlying issue of inflammation.1
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